CDH1 for Hereditary Diffuse Gastric Cancer
Test: CDH-1 gene mutation analysis for Gastric cancer- 1. Hereditary Diffuse Gastric cancer ( autosomal dominant) Significance of this test: CDH1 gene belongs to a family of genes called Cadherin(s)...
View ArticlePALB2 for Breast Cancer
Test: PALB2 for Breast Significance of this test: Assess prevalance of PALB2 mutation in pt with hereditary breast cancer Assess risk of breast and pancreatic cancer in patient with PALB2 mutation...
View ArticleBRCA for Breast Cancer
Test: BRCA for Breast Cancer Significance of this test: “Risk of cancer if the test is positive BRCA 1 + have 57-87 % risk of having breast cancerand BRCA 1 positive have 39 to 40 %risk of having...
View ArticleTP53 for Breast Cancer
TP53 for Breast Cancer Significance of this test: Pt with family history of Li Fraumeni Syndrome Germline (heritable) mutations in the TP53 gene1 predispose individuals to various tumors (early onset...
View ArticleAPC gene mutation for Gastric Cancer
Test: HER2 over expression, HER2 amplification, Beta Catenin mutation, APC gene mutation for Gastric cancer-2. ( histological classification)- Intestinal Gastric cancer Significance of this test: 1)...
View ArticleCHEK2 for Prostrate Cancer
Test: CHEK2 for PROSTATE Significance of this test: CHEK 2 is involved in DNA damage/signalling pathways as it encodes Serine/Theronine protein kinase. It regulates function of p53 and BRCA1....
View ArticleBRAF Mutation Analysis
BRAF Mutation Analysis for Melanoma Significance of this test: Mutations in the BRAF Have been found in approximately 40% of the primary cuatneous melanomas. Mutation in BRAF is an early event in the...
View ArticleBRAF Mutation
Test: BRAF Mutation Analysis for Ovarian Cancer Significance of this test: Mutation of BRAF in various types of ovarian cancer High Grade Serous (Type II) < 1% Low Grade Serous (Type I) 24-33% Clear...
View ArticleKRAS
<div class=”boxed”> This text is enclosed in a box. </div> Test: KRAS Mutation Analysis for Colon Cancer Significance of this test: Tumor harboring the KRAS mutation are not reponsive to...
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